Kid-Approved Cheesy Beef & Biscuit Casserole Recipe

Comfort food takes center stage with this mouthwatering cheesy beef & biscuit casserole that promises to satisfy even the hungriest appetites.

Layers of savory ground beef meld perfectly with melted cheese and tender biscuit pieces.

Every forkful bursts with rich, hearty flavors that remind you of home-cooked goodness.

The dish combines classic ingredients in a simple yet irresistible way.

Warm, gooey, and packed with protein, this casserole delivers maximum taste with minimal effort.

Hearty meals like these bring people together around the dinner table.

Get ready to become the dinner hero with this crowd-pleasing recipe that’s sure to earn rave reviews.

Quick Recipe Overview

Prep Time: 10 minutes

Cook Time: 30 minutes

Total Time: 40 minutes

Calories: 366 kcal

Servings: 7

Cheesy Beef & Biscuit Casserole: Ingredient List

• Ground Beef: Provides hearty, rich flavor and substantial protein for the main dish, choose lean cuts for less grease and better texture.
• Worcestershire Sauce: Adds deep umami complexity and enhances the meat's natural savory notes, look for authentic brands with robust ingredients.

• Ketchup, Brown Sugar: Creates a tangy-sweet base sauce that balances the meat's richness, select high-quality ketchup for better depth.
• Mustard, Garlic Powder, Onion Powder: Contributes layered spice and aromatic undertones, opt for fresh, fragrant spice blends.
• Salt: Elevates and harmonizes all other flavor profiles, use sea salt or kosher salt for cleaner taste.
• Water: Helps create moisture and blend sauce ingredients smoothly.

• Refrigerated Biscuits: Provides quick, fluffy texture and convenient base for casserole, select buttery varieties for richer taste.
• Cheddar Cheese: Delivers creamy, sharp topping that melts beautifully, choose sharp or extra-sharp for more pronounced flavor.
• Cooking Spray: Ensures easy pan release and prevents sticking, use neutral vegetable-based sprays.

Kitchen Equipment for Cheesy Beef Casserole Prep

• Large Skillet: Perfect for browning ground beef evenly and developing rich flavors.
• Medium Bowl: Essential for mixing biscuit pieces with seasoned meat.
• 9×13 Baking Pan: Provides ideal space for layering and baking the casserole.
• Cooking Spray: Ensures easy release and prevents sticking.
• Wooden Spoon or Spatula: Great for stirring and mixing ingredients.
• Measuring Cups and Spoons: Helps maintain accurate ingredient proportions.
• Sharp Knife: Useful for cutting or quartering biscuits.

Instructions for Cheesy Biscuit-Topped Casserole

• Oven Prep Cozy Kitchen Warmup

Warm your kitchen by setting the oven to a toasty 350°F. Lightly coat a large baking dish with non-stick spray to ensure easy serving and cleanup.

• Meaty Magic

Brown ground beef in a skillet, creating delicious caramelized edges. Drain away any extra grease to keep the dish light and delectable.

• Flavor Explosion

Blend savory seasonings into the beef, creating a mouthwatering sauce that’ll make taste buds dance. Let the mixture simmer and bubble with rich, complex flavors.

• Biscuit Blend

Gently fold chunky biscuit pieces into the beef mixture, allowing each piece to soak up the delicious sauce. The combination creates a hearty, comforting texture.

• Cheesy Crown

Sprinkle a generous layer of sharp cheddar cheese across the top, ensuring every bite will have a melty, golden finish.

• Baking Transformation

Slide the casserole into the heated oven and let it bake until the top turns a beautiful golden brown and the cheese becomes irresistibly bubbly.

• Serve and Enjoy

Pull out the steaming casserole and serve immediately, letting everyone dig into this crowd-pleasing meal that feels like a warm hug.

Casserole Tweaks: Tips to Try

• Swap cheddar with pepper jack, mozzarella, or a spicy blend to create unique taste profiles that match your family's preferences.
• Sneak in diced bell peppers, mushrooms, or frozen mixed vegetables during the meat cooking stage to add extra nutrition and color.
• Kick up the heat by adding red pepper flakes, a dash of sriracha, or cayenne pepper for those who love a zesty kick in their comfort food.
• Assemble the entire casserole earlier in the day and refrigerate, then bake just before serving for a stress-free meal preparation.

Ways to Serve Cheesy Beef & Biscuit Casserole

• Serve with Fresh Salad: Pair the casserole with a crisp green salad topped with cherry tomatoes and a light vinaigrette to balance the richness of the cheesy beef dish.
• Garnish with Herbs: Sprinkle chopped fresh parsley or chives over the top for a burst of color and added freshness that complements the hearty flavors.
• Side of Roasted Vegetables: Add a colorful medley of roasted seasonal vegetables like broccoli, carrots, or zucchini to create a well-rounded and nutritious meal.
• Cool Down with Sour Cream: Offer a dollop of cool sour cream on the side to provide a tangy contrast to the warm, cheesy casserole.

Storing Your Biscuit Casserole Smartly

• Refrigerate Wisely: Store leftover casserole in an airtight container within two hours of cooking, keeping it fresh in the refrigerator for up to 3-4 days.
• Freeze for Later: Package individual portions or the entire casserole in freezer-safe containers, maintaining quality for up to 2 months when properly sealed.
• Reheat with Care: Warm refrigerated portions in the oven at 350°F for 15-20 minutes, ensuring the internal temperature reaches 165°F to guarantee food safety and restore crispy texture.
• Prep Ahead Strategy: Assemble the casserole ingredients the night before, cover tightly, and refrigerate until ready to bake, saving time during busy weeknight dinners.

Hearty Beef & Biscuit Casserole Recipe

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4.7 from 12 reviews

• Total Time: 40 minutes
• Yield: 7 1x

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Description

Hearty cheesy beef & biscuit casserole combines ground beef, melted cheese, and flaky biscuits in one comforting dish. Families will savor this simple midwestern favorite that provides warmth and satisfaction with each delicious bite.

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Ingredients

Scale 1x2x3x

• 1 lb (454 g) ground beef
• 12 oz (340 g) biscuits, cut into quarters
• 1 cup (240 ml) cheddar cheese, shredded
• ¾ cup (180 ml) ketchup
• ¼ cup (60 ml) water
• 3 tsp brown sugar
• 2 tsp Worcestershire sauce
• 2 tsp mustard
• 1 tsp garlic powder
• 1 tsp onion powder
• ¼ tsp salt

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Instructions

1. Preheat: Warm the oven to 350°F (177°C) and lavishly spray a 9×13-inch baking dish with cooking spray.
2. Sizzle & Season: In a skillet, brown the ground beef over medium heat, crumbling into tiny pieces until fully cooked. Drain excess fat, then blend ketchup, water, brown sugar, Worcestershire sauce, mustard, garlic powder, onion powder, and salt into the meat. Simmer for 5 minutes to intensify flavors.
3. Combine & Layer: Cool the seasoned beef mixture slightly, then slice biscuits into quarters and fold gently into the meat. Spread the biscuit-beef medley evenly across the prepared baking dish, ensuring uniform coverage.
4. Cheese Finale: Blanket the casserole with a generous layer of shredded cheddar cheese, covering every inch of the surface.
5. Bake & Rest: Slide the dish into the preheated oven and bake for 28-30 minutes until the top achieves a golden-brown hue and cheese melts completely. Let the casserole rest for 3-5 minutes before serving piping hot.

Notes

• Meat Preparation Tip: Drain beef thoroughly to prevent excess grease, ensuring a crisp and not soggy casserole texture.
• Seasoning Secret: Simmer beef mixture for full flavor development, allowing spices to blend and intensify taste profiles.
• Cheese Coverage Trick: Spread cheese evenly across the entire surface for consistent melting and golden-brown finish.
• Resting Recommendation: Let casserole rest briefly after baking to set ingredients and enhance overall dish stability.

• Prep Time: 10 minutes
• Cook Time: 30 minutes
• Category: Breakfast, Dinner
• Method: Baking
• Cuisine: American

Nutrition

• Serving Size: 7
• Calories: 366
• Sugar: 5 g
• Sodium: 658 mg
• Fat: 22 g
• Saturated Fat: 10 g
• Unsaturated Fat: 9 g
• Trans Fat: 1 g
• Carbohydrates: 24 g
• Fiber: 1 g
• Protein: 18 g
• Cholesterol: 73 mg